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. 2021 Jun 22;4:769. doi: 10.1038/s42003-021-02316-6

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — The Environmental influences on Child Health Outcomes (ECHO) program, created in 2016, is an NIH-funded national program that supports existing observational and intervention studies to answer important questions about key developmental areas, including pre-, peri-, and early postnatal outcomes, airway conditions, obesity, and neurodevelopment. Exposures of interest include nutrition, tobacco smoke, pollutants, physical activity, drug usage, and stress. The ECHO program offers a unique platform and opportunity in which to explore the health effects of exposures, including more contemporaneous ones, that are present or have far-reaching consequences across generations.