Table 4.
Coefficient of drug interaction (CDI) for chlorhexidine and nystatin combinations in the Candida albicans and Streptococcus mutans biofilm assay according to the treatment used
| Treatment | CDI | |
|---|---|---|
| C1 | C2 | |
| Chlorhexidine/30 min/nystatin | 2.105 | 2.272 |
| Nystatin/30 min/chlorhexidine | 1.986 | 2.280 |
| Chlorhexidine/1 min/nystatin | 1.905 | 1.536 |
| Nystatin/2 min/chlorhexidine | 1.695 | 1.452 |
| Chlorhexidine/10 min/nystatin | 2.401 | 2.285 |
| Nystatin/10 min/chlorhexidine | 2.401 | 2.285 |
| Chlorhexidine/nystatin single | 1.570 | 1.517 |
C1 2 μg/mL chlorhexidine and 1 μg/mL nystatin, C2 1 μg/mL chlorhexidine and 0.5 μg/mL nystatin