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. 2021 Jun 22;11:13043. doi: 10.1038/s41598-021-90684-8

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A–D) Representative scanning electron micrographs of fibrin networks (prepared form PPP) from a healthy individual and psoriatic patients. (A) A typical fibrin network of a healthy 47-year-old female individual. (B–D) Fibrin networks of psoriatic individuals. (B) A fibrin network of a 45-year-old female individual with low PsA activity and mild skin involvement. (C) A fibrin network of a 40-year-old male individual with moderate PsA activity and mild skin involvement. (D) A fibrin network of a 49-year-old male individual with high PsA activity and moderate skin involvement.