| Reaction time (R) |
min |
Activation phase: Time from start of test to first detectable fibrin formation (amplitude of 2 mm). Influenced by concentration of coagulation factors. |
| Kinetics (K) |
min |
Amplification phase: Time taken to form a clot with a certain level of strength (amplitude of 20 mm). Influenced by fibrinogen concentration and to a lesser extent, platelet function. |
| Alpha angle (A) |
deg |
Propagation phase: The angle measures the maximal speed of thrombin generation and fibrin formation and cross-linking. Influenced by fibrinogen concentration and to a lesser extent, platelet function. |
| Maximum amplitude (MA) |
mm |
Termination phase: Maximum mechanical strength/stiffness of clot. Influenced by fibrin cross-linking, platelet count and platelet glycoprotein IIb/IIIa interactions. |
| Maximum rate of thrombus generation (MRTG) |
dynes/cm2/s |
First derivative of the velocity of the increase in clot strength based on the change in the elastic modulus, G, where G = (5000MA)/(100-MA). |
| Time to maximum rate of thrombus generation (TMRTG) |
min |
Time interval observed before maximum speed of clot growth. |
| Total thrombus generation (TTG) |
dynes/cm2
|
Total area under the velocity curve, representing the clot strength generated during clot growth. |
