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. 2021 Jun 9;15:686932. doi: 10.3389/fnins.2021.686932

TABLE 3.

Linear regression analysis of AL elongation association with baseline data and RCRPS parameters.

Group Parameter Univariate model
Multivariate model
Beta (95% CI) P value Beta (95% CI) P value
OK Age (year) −0.070 (−0.106 to −0.034) 0.001 −0.044 (−0.078 to −0.011) 0.014
Gender (boys) 0.035 (−0.105 to 0.174) 0.628 \ \
Baseline AL (mm) −0.189 (−0.275 to −0.103) <0.001 −0.066 (−0.161 to 0.029) 0.183
Baseline SE (D) 0.072 (0.006 to 0.138) 0.040 Removed
Half_x (mm) 0.276 (0.154 to 0.398) <0.001 0.186 (0.064 to 0.309) 0.005
Half_y (D) −0.037 (−0.189 to 0.116) 0.640 \ \
Sum4 (D*mm2) −0.011 (−0.017 to −0.004) 0.003 Removed
Sum7 (D*mm2) −0.002 (−0.004 to 0.000) 0.114 \ \
Half_x – PR (mm) 0.145 (0.058 to 0.231) 0.002 Removed
MFCL Age (year) −0.045 (−0.076 to −0.014) 0.008 −0.045 (−0.076 to −0.014) 0.008
Gender (boys) 0.016 (−0.086 to 0.118) 0.757 \ \
Baseline AL (mm) −0.015 (−0.092 to 0.062) 0.710 \ \
Baseline SE (D) 0.013 (−0.044 to 0.069) 0.666 \ \
Half_x (mm) 0.046 (−0.126 to 0.219) 0.600 \ \
Half_y (D) −0.014 (−0.087 to 0.060) 0.716 \ \
Sum4 (D*mm2) −0.002 (−0.006 to 0.002) 0.395 \ \
Sum7 (D*mm2) 0.000 (−0.001 to 0.001) 0.453 \ \
Half_x – PR (mm) 0.033 (−0.075 to 0.141) 0.554 \ \
Combined data Age (year) −0.058 (−0.083 to −0.034) <0.001 −0.045 (−0.067 to −0.023) <0.001
Gender (boys) 0.019 (−0.069 to 0.107) 0.668 \ \
Baseline AL (mm) −0.109 (−0.171 to −0.048) 0.001 −0.047 (−0.102 to 0.007) 0.095
Baseline SE (D) 0.050 (0.006 to 0.095) 0.031 Removed
Half_x (mm) 0.209 (0.123 to 0.295) <0.001 0.161 (0.082 to 0.241) <0.001
Half_y (D) 0.022 (−0.040 to 0.084) 0.485 \ \
Sum4 (D*mm2) −0.006 (−0.010 to −0.002) 0.003 Removed
Sum7 (D*mm2) −0.001 (−0.002 to 0.000) 0.290 \ \
Half_x – PR (mm) 0.123 (0.060 to 0.186) <0.001 Removed

CI, confidence interval; AL, axial length; RCRPS, relative corneal refractive power shift; SE, spherical equivalent, D, diopter; OK, orthokeratology; MFCL, multifocal soft contact lens; Combined data, OK and MFCL groups together; Half_x, the corneal eccentric location where RCRPS reached the half peak value; Half_y, half of the RCRPS peak value; Sum4, the integrated value of the RCRPS located within an area of 4-mm diameter; Sum7, the integrated value of the RCRPS located within an area of 7-mm diameter; PR, pupil radius; Removed, Based on the Akaike Information Criterion, the factor was not selected for analysis in the multivariate model. Bolded values indicate p < 0.05.