Figure 5.
Involvement of ERK activation in the effect of rhCCL20 on macrophage-like cells. (A) Macrophage-like cells were stimulated by 50 ng/ml rhCCL20 for the indicated time course. The treatment for 120 minutes induced the phosphorylation of ERK. (B) Pretreatment of macrophage-like cells with 10 µM U0126 for 120 minutes blocked the rhCCL20 induced-CD163 expression. DMSO was added as a negative control.