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. 2021 Jun 9;12:645881. doi: 10.3389/fendo.2021.645881

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Copyright © 2021 Farrash, Phillips, Britton, Qi, Koch, Wilkinson, Smith and Atherton

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Temporal change in concentration of plasma myokines and area under the curve (AUC) before and after exercise training. (A) Brain-derived neutrophic factor (BDNF); (B) Fractalkine; (C) Interlukin-6 (IL-6); (D) Secreted protein acidic and rich in cysteine (SPARC); Baseline (BL). Values are means±SD. Analysis via two-way ANOVA with Sidak’s post hoc test. Main effects are shown in the text box. *P<0.05, ***P<0.001, NS, Not Significant. a=significant change from BL. b= significant change from 0h. Non-underlined symbols represent within group differences. Underlined symbols represent between groups differ.