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. 2021 Jun 9;12:689387. doi: 10.3389/fendo.2021.689387

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Copyright © 2021 Gregoric, Groselj, Bratina, Debeljak, Zerjav Tansek, Suput Omladic, Kovac, Battelino, Kotnik and Avbelj Stefanija

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Modified WHO growth charts* display both case patients. (A) Case patient 1—length for age and weight for age; (B): Case patient 1—BMI for age, (C): Case patient 2—length for age and weight for age, (D): Case patient 2—BMI for age; BLUE ARROW marks the onset of setmelanotide treatment of case patient 1. *Original WHO growth charts were modified due to restrictions of scale and age.