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Schematic representation of POMC-derived peptides and genetic variants associated with autosomal recessive POMC deficiency. ACTH, corticotropin; β-LPT, lipotropin β; γ-LPT, lipotropin γ; α-MSH, melanotropin α; β-MSH, melanotropin β; γ, MSH, melanotropin γ; NPP, N-terminal peptide of proopiomelanocortin; SP, signal peptide.
