Table 3.
Laboratory values of case patient 2.
| Biochemistry/Age | 9 days | 3 weeks | 7 months | 11 months | 20 months | 2.5 years | 3.5 years |
|---|---|---|---|---|---|---|---|
|
TSH [mU/L]
(0.59–4.23) |
3.83 | 7.84 | 5.34 | 0.92* | 3.24* | 3.90* | |
|
fT4 [pmol/L]
(11.7–22.5) |
14.9 | 15.0 | 8.2 | 14.8* | 11.3* | 14.9* | |
|
fT3 [pmol/L]
(3.79–6.05) |
4.0 | 4.8 | 5.9 | 6.7* | 5.74* | 4.86* | |
| IGF-1 [μg/L] | 100 (20–159) |
213 (19.5–132.3) |
174 (22.2–145.4) |
186 (25.9–164.2) |
|||
| IGFBP3 [mg/L] | 4.48 (1.37–4.30) |
4.49 (1.22–3.72) |
6.10 (1.39–4.15) |
4.40 (1.55–4.56) |
|||
| GH (basal/peak)† [μg/L] | 0.73/3.49 | 0.34 | |||||
| LH (basal/peak) [U/L] | 0.2/8.5 | ||||||
| FSH (basal/peak) [U/L] | 5.2/26.3 | ||||||
| Cortisol (basal/peak)‡ [nmol/L] | <27.5/<27.5 | ||||||
|
ACTH [pmol/L]
(<10.20) |
<1.11 | ||||||
| PRA [μg/L/h] | 8.72 | ||||||
| Insulin (basal/2 h)§ [mU/L] | 9.4 | 3.5/238.0 | |||||
| Glucose (basal/2 h)§ [mmol/L] | 4.2 | 4.0/6.7 | |||||
|
AST [μkat/L]
(<0.52) |
1.25 | 0.55 | |||||
|
ALT [μkat/L]
(<0.57) |
1.09 | 0.78 | |||||
|
ϒGT [μkat/L]
(<0.63) |
1.40 | 0.21 | |||||
|
Androstendion [nmol/L]
(0.7–10.8)¶ |
<0.1 | <0.1 | |||||
|
DHEA-S [μmol/L]
(3.6–12.9)¶ |
0.09 | <0.08 | |||||
|
SHBG [nmol/L]
(18–114)¶ |
29 | ||||||
| 17-OHP [nmol/L] | 0.17 | ||||||
|
Total cholesterol
[mmol/L] (<5.2) |
2.8 | ||||||
| LDL [mmol/L] (<3.4) | 1.7 | ||||||
| HDL [mmol/L] (>1.3) | 0.8 | ||||||
| Triglycerides [mmol/L] (<1.7) | 0.7 |
*thyroid function with L-thyroxin supplementation; † Peak value was obtained after stimulation with arginine; ‡ Peak value was obtained 30 min after intravenous stimulation with synthetic ACTH 1 µg; § values were obtained with oral glucose tolerance test; ¶ normal range in adults.
The reference values are stated in brackets.