Incidence as a 3-year moving average of invasive pneumococcal disease incidence per 100 000 age-specific population from Jan 1, 2006, to Dec 31, 2018
Shown is vaccine serotype invasive pneumococcal disease in infants (A), 1–4-year-old children (C) 5–14-year-old children (E), and individuals aged 15 years and older (G) and non-vaccine serotype invasive pneumococcal disease in infants (B), 1–4-year-old children (D) 5–14-year-old children (F), and individuals aged 15 years and older (H). Negative binomial model fit for Jan 1, 2006, to Dec 31, 2011 (before PCV) and predicted counterfactual therefrom for Jan 1, 2014, to Dec 31, 2018 (after PCV). Negative binomial model fit for Jan 1, 2014, to Dec 31, 2018. PCV=pneumococcal conjugate vaccine. Vertical dashed line indicates introduction of PCV13.