Table 3.
Characteristics of women without PCOS and with the low, moderate, and high ovarian response (n=5129).
| Ovarian response | Low (n = 805) | Moderate (n = 3305) | High (n = 1019) | P value1 |
|---|---|---|---|---|
| Age (y) | 34.8 ± 5.3 | 31.4 ± 4.3 | 29.4 ± 3.7 | <0.00001 |
| BMI (kg/m2) | 22.0 ± 2.7 | 21.6 ± 2.6 | 21.3 ± 2.6 | <0.0001 |
| Menarche age (y) | 13.9 ± 1.3 | 13.9 ± 1.4 | 13.9 ± 1.4 | NS |
| Infertility years (y) | 3.8 ± 3.6 | 3.3 ± 2.8 | 3.0 ± 2.4 | <0.00001 |
| Bleeding duration (days) | 5.7 ± 1.4 | 5.8 ± 1.3 | 6.0 ± 1.5 | <0.00001 |
| Menstrual cycle | 28 (27, 30) | 30 (28, 30) | 30 (28, 32) | <0.00001 |
| Gravidity (≥1) | 483 (60%) | 1859 (56%) | 545 (54%) | <0.05 |
| Parity (≥1) | 232 (29%) | 676 (20%) | 144 (14%) | <0.00001 |
| Antral follicle count | 6.8 ± 4.3 | 12.4 ± 4.6 | 16.0 ± 4.5 | <0.00001 |
| Basal hormone levels2 | ||||
| FSH mIU/ml | 9.7 ± 5.4 | 6.9 ± 2.2 | 6.0 ± 1.5 | <0.00001 |
| Estradiol pmol/l | 135 ± 100 | 120 ± 68 | 112 ± 58 | <0.00001 |
| Progesterone nmol/l | 1.1(0.7,1.5) | 1.1(0.8,1.5) | 1.1 (0.8,1.4) | NS |
| LH mIU/ml | 5.0 ± 3.6 | 4.9 ± 2.3 | 5.6 ± 2.7 | <0.00001 |
| AMH ng/ml | 1.0 ± 1.0 | 2.8 ± 1.9 | 5.0 ± 2.5 | <0.00001 |
| Testosterone nmol/l | 0.7 (0.4,1.0) | 0.7 (0.5,1.0) | 0.8 (0.5,1.1) | NS |
| Gonadotropin dose (IU) | 1592 ± 894 | 2139 ± 705 | 1970 ± 637 | <0.00001 |
| GnRH antagonist | 258 (32%) | 1534 (47%) | 353 (35%) | <0.00001 |
NS, not significant (P > 0.05). Mean ± SD or median (IQR) as appropriate.
1χ2 or ANOVA test as appropriate.
2Day 2 or day 3 of the menstrual cycle.