Table 2.
Circulating cytokine concentrations among malaria slide negative participants, participants with asymptomatic malaria and patient with clinical malaria.
| Slide negative participants | Asymptomatic malaria | Patients withclinical malaria | p-value | Dunn’s test | |||
|---|---|---|---|---|---|---|---|
| n=235 | n=126 | n=118 | SN versus AM | SN versus CM | AM versus CM | ||
| IL-6 | 1.2 (0.7-2.4) | 3.4 (2.1-12.2) | 69.2 (22.2-303.0) | <.0001 | <.0001 | <.0001 | <.0001 |
| IL-10 | 3.8 (2.4-7.7) | 56.2 (29.3-132.0) | 439.0 (140.0-1,333.0) | <.0001 | <.0001 | <.0001 | <.0001 |
| TNF-a | 25.28 (20.2-30.6) | 39.57 (30.6-53.5) | 71.6 (42.5-121.0) | <.0001 | <.0001 | <.0001 | <.0001 |
| IFN-y | 2.1 (2.1-2.1) | 2.1 (2.1-6.8) | 42.9 (25.1-78.1) | <.0001 | .006 | <.0001 | <.0001 |
SN, slide negative; AM, asymptomatic malaria; CM, clinical malaria.
Data is presented as median (25-75 IQR). Significance value calculated using a Kruskal Wallis test with post-hoc Dunn’s test. Cytokine concentrations are reported in pg/mL.