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. 2021 Jun 9;12:681338. doi: 10.3389/fphar.2021.681338

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Copyright © 2021 Mao, Zhu, Nie, Yu and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Levobupivacaine represses survival of gastric cancer cells in vitro. (A) The GES-1, HGC27, and SGC7901 cells were treated with levobupivacaine at the indicated concentrations. MTT assays for cell viability analysis. (B–E) HGC27 and SGC7901 cells were treated with saline or levobupivacaine (2 mM). (B) MTT assays for cell viability analysis. (C,D) Edu assays for cell proliferation analysis. (E,F) Flow cytometry analysis of apoptosis. The experiments were performed independently three times (mean ± SD, **p < 0.01).