Table 2.
PD-1 SNPs.
| SNP | Polymorphism | Location | Ancestral allele | MAF | Genotype | Genotype frequency (%) | |
|---|---|---|---|---|---|---|---|
| Control* | Study | ||||||
| PD1.1 | rs36084323 | promoter | G | 0.15 (T) | G/GA/GA/A | 97 3 0 |
99 1 0 |
| PD1.3 | rs11568821 | intron | C | 0.04 (T) | A/AA/GG/G | 2 20 78 |
0 28 72 |
| PD1.5 | rs2227981 | synonymous | G | 0.35 (A) | C/CC/TT/T | 38 44 18 |
46 48 6 |
| PD1.6 | rs10204225 | 3’UTR | G | 0.03 (A) | A/A A/G G/G |
0 0 100 |
0 20 80 |
| PD1.9 | rs2227982 | missense | G | 0.14 (A) | T/T C/T C/C |
0 3 97 |
0 5 95 |
MAF, Minor allele frequency; SNP, Single-nucleotide polymorphism; UTR, untranslated regions.
*Caucasian population.