Table 1.
Interactions among the hexadecameric complex formed by nsp12 and nsp7/nsp8 of SARS-CoV-2 as obtained from UCSF Chimera software. The distance is referred to the distance between the centroid of the selected residues. The bond length (Å) is defined as the distance between the atoms involved in the hydrogen bonding.
| nsp12 | nsp7-8 | Type of contact | Overlap | Distance | Bond length |
|---|---|---|---|---|---|
| Gly897 | Asn69 (nsp7) | non-polar | 1.932 | 1.368 | – |
| Gly510 | Cys72 (nsp7) | non-polar | 1.165 | 2.135 | – |
| Met899 | Arg111 (nsp8) | non-polar | 1.002 | 2.518 | – |
| Trp509 | Arg96 (nsp8) | non-polar | 0.742 | 3.018 | – |
| Leu900 | Arg111 (nsp8) | non-polar | 0.727 | 3.033 | – |
| Thr409 | Met174 (nsp8) | non-polar | 0.718 | 3.042 | – |
| Lys411 | Asn136 (nsp8) | non-polar | 0.654 | 2.866 | – |
| Arg513 | Glu73 (nsp7) | non-polar | 0.641 | 2.659 | – |
| Thr409 | Asn136 (nsp8) | polar | – | – | 2.767 |
| Trp509 | Asn104 (nsp8) | polar | – | – | 2.681 |