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. 2021 Jun 28;18(6):449–461. doi: 10.11909/j.issn.1671-5411.2021.06.006

Table 1. Baseline demographic and clinical characteristics of patients with non-severe bleeding and severe bleeding in the training group.

Variables Non-severe bleeding (n = 345) Severe bleeding (n = 138) P-value
Data are presented as means ± SD or n (%). *Presented as median (interquartile range).
Age, yrs 64.0 (61.0−71.0)* 63.0 (60.5−72.5)* 0.204
Male 260 (75.4%) 89 (64.5%) < 0.05
Body mass index, kg/m2 25.5 ± 4.3 25.7 ± 3.9 0.625
Hypertension 226 (65.5%) 83 (60.1%) 0.267
Hyperlipidemia 57 (16.5%) 26 (18.8%) 0.542
Diabetes mellitus 108 (31.3%) 40 (29.0%) 0.618
Prior myocardial infarction 43 (12.5%) 13 (9.4%) 0.345
Prior percutaneous coronary intervention 25 (7.2%) 9 (6.5%) 0.779
Stroke 77 (22.3%) 24 (17.4%) 0.400
Aspirin 227 (65.8%) 108 (78.3%) < 0.05
Clopidogrel 93 (27.0%) 52 (37.7%) < 0.05
Preoperative laboratory test
 Hemoglobin, g/L 132.1 ± 15.1 134.6 ± 14.7 0.103
 Hematocrit, % 39.2 ± 4.4 38.5 ± 4.1 0.100
 Platelet count, × 109/L 214.9 ± 67.3 211.3 ± 63.9 0.597
 Alanine transaminase, U/L 24.8 (15.4−40.5)* 29.6 (21.2−41.2)* 0.077
 Total bilirubin, μmol/L 11.4 ± 4.2 12.2 ± 4.4 0.064
 Serum creatinine, μmol/L 71.0 (62.0−81.0)* 75.0 (64.5−81.5)* 0.183
 Prothrombin time, s 11.3 ± 1.0 11.3 ± 0.6 0.624
 Activated partial thromboplastin time, s 30.1 (28.4−32.2)* 31.2 (28.8−33.0)* < 0.05
 Fibrinogen, g/L 3.4 ± 0.7 3.4 ± 0.6 0.502
Postoperative laboratory test
 Hemoglobin, g/L 114.1 ± 16.1 114.5 ± 19.1 0.861
 Hematocrit, % 34.2 ± 4.4 33.3 ± 5.2 0.058
 Platelet count, × 109/L 178.0 ± 48.9 162.1 ± 47.6 < 0.05
 Alanine transaminase, U/L 25.1 (16.2−46.5)* 31.0 (21.4−43.3)* 0.260
 Total bilirubin, μmol/L 15.2 (11.1−19.6)* 16.5 (12.3−22.0)* < 0.05
 Serum creatinine, μmol/L 77.5 ± 18.1 85.3 ± 20.3 < 0.05
 C-reactive protein, mg/L 17.4 (7.0−66.0)* 34.3 (6.5−144.8)* < 0.05
 Cardiac troponin I, ng/mL 1.0 (0.5−1.8)* 1.2 (0.5−2.3)* 0.069
 Creatine kinase-MB isozyme, U/L 27.0 (22.0−33.0)* 25.0 (21.0−31.0)* 0.123
 Prothrombin time, s 12.6 (12.1−13.3)* 12.6 (12.0−13.5)* 0.913
 Activated partial thromboplastin time, s 32.7 (29.9−36.6)* 32.6 (30.3−36.1)* 0.536
 Fibrinogen, g/L 2.4 ± 0.5 2.2 ± 0.6 < 0.05
 N-terminal pro-B-type natriuretic peptide, pg/mL 337.0 (128.0−826.0)* 304.7 (115.0−785.0)* 0.482
Cell saver transfusion, mL 450.0 (300.0−800.0)* 600.0 (410.0−1144.0)* < 0.05
Red blood cells, U 0 0 0.185
Plasma, mL 400.0 (0.0−400.0)* 400.0 (0.0−400.0)* 0.302
Postoperative chest drain loss, mL/24 h 729.0 (628.0−856.0)* 1202.5 (1105.0−1350.0)* < 0.05