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. 2021 Jun 23;49(6):1133–1147. doi: 10.1007/s15010-021-01644-3

Table 1.

Current clinical trials related to vitamin therapy in COVID-19 patients

Vitamins NCT number Study title Phase Age Status*
Vitamin A NCT04900415 Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction 2 18 years and older Recruiting
Vitamin D NCT04344041 COVID-19 and vitamin D supplementation: a multicenter randomized controlled trial of high dose versus standard-dose vitamin d3 in high-risk COVID-19 patients (CoVitTrial) 3 70 years and older Completed
NCT04709744 Impact of vitamin D level and supplement on SLE patients during COVID-19 pandemic NA 18–80 years Completed
NCT04535791 Efficacy of vitamin D supplementation to prevent the risk of acquiring COVID-19 in healthcare workers (COVID-19) 3 18- 70 years Recruiting
NCT04386850 Oral 25-hydroxyvitamin D3 and COVID-19 2/3 18–75 years Recruiting
NCT04411446 Cholecalciferol to improve the outcomes of COVID-19 patients 4 18 years and older Recruiting
NCT04385940 Vitamin D and COVID-19 management 3 17 years and older Recruiting
NCT04482673 Vitamin D supplementation in the prevention and mitigation of COVID-19 infection 4 50 years and older Recruiting
NCT04883203 The effect of vitamin D supplementation on COVID-19 recovery (COVID-VITD) 3 18–70 years Completed
NCT04525820 High dose vitamin-d substitution in patients with COVID-19: a randomized controlled, multi-center study NA 18 years and older Recruiting
NCT04552951 Effect of vitamin D on morbidity and mortality of the COVID-19 (COVID-VIT-D) 4 Child, adult, older adult Recruiting
NCT04411446 Cholecalciferol to improve the outcomes of COVID-19 patients (CARED) 4 18 years and older Recruiting
NCT04636086 Effect of vitamin D on hospitalized adults with COVID-19 infection 4 18 years and older Recruiting
NCT04733625 The effect of vitamin D therapy on morbidity and mortality in patients with SARS-CoV 2 infection NA 18 years and older Completed
NCT04344041 Covid-19 and vitamin D supplementation: a multicenter randomized controlled trial of high dose versus standard-dose vitamin d3 in high-risk COVID-19 patients (CoVitTrial) 3 65 years and older Completed
NCT04459247 Short term, high dose vitamin d supplementation for COVID-19 (SHADE) NA 18 years and older Active, not recruiting
NCT04621058 Efficacy of vitamin D treatment in mortality reduction due to COVID-19 3 Child, adult, older adult Recruiting
NCT04502667 Efficacy of vitamin D treatment in pediatric patients hospitalized by COVID-19 3 1 month to 17 years Recruiting
Vitamin C NCT04401150 Lessening organ dysfunction with vitamin C-COVID-19 3 18 years and older Recruiting
NCT04357782 Administration of intravenous vitamin c in novel coronavirus infection (COVID-19) and decreased oxygenation (AVoCaDO) 1/2 18–99 years Completed
NCT04344184 Safety study of early infusion of vitamin c for treatment of novel coronavirus acute lung injury (SAFE EVICT CORONA-ALI) 2 18 years and older Recruiting
NCT04682574 Role of mega dose of vitamin c in critical COVID-19 patients NA Child, adult, older adult Recruiting
NCT04363216 Pharmacologic ascorbic acid as an activator of lymphocyte signaling for COVID-19 treatment 2 18 years and older Not yet recruiting
NCT04710329 High-dose vitamin c treatment in critically ill COVID-19 patients NA 18–99 years Completed

*Please refer to http://clinicaltrials.gov for more details.