Figure 1. Rutin exhibited reduced viability in HeLa cancer cells after tretment with increasing doses of rutin for 24 h.

(A) MTT assay to examine cell viability. (B) HeLa cells were exposed to varying doses of 5-FU (1–5 μM) for 24 h. (C) HeLa cells were treated with combined dose of rutin (0–200 μM) + 5-FU (5 μM) to assess the synergistic effect. % cell viability (assesses by MTT assay) was normalized against untreated cells (control). SEM and mean of three independent experiments were presented: *P<0.01, **P<0.001, in comparison to related control value.