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. 2021 Jun 21;41(6):BSR20210670. doi: 10.1042/BSR20210670

Figure 4. Effect of rutin on cell cycle modulation and mRNA expression of its associated genes.

Figure 4

(A) Cell cycle distribution in rutin-treated HeLa cancer cells after being exposed for 24 h. (B) Graph showing the expression level of cell cycle regulatory gene (Cyclin D1 and CDK4) analyzed using RT-PCR (C,D) Graph showing the expression level of apoptotic genes (p53, Bax, Bcl-2, pRb) analyzed using RT-PCR SEM and mean of three independent experiments were presented: *P<0.01, **P<0.001, in comparison to related control value.