Skip to main content
. 2021 Jun 22;14(6):e241289. doi: 10.1136/bcr-2020-241289

Table 3.

Phenotypic features of fatal insomnia

Sleep and behavioural

  •  Insomnia

  •  Sleep state dissociation with dream enactment

  •  Altered vigilance

  •  Progressive dementia

Motor

  •  Tremor

  •  Myoclonus

  •  Ataxia

  •  Dysarthria

  •  Dysphagia

  •  Diplopia

  •  Pyramidal signs

  •  Positive Babinski reflex

  •  Gait apraxia
Dysautonomia

  •  Hypertension

  •  Evening fever

  •  Perspiration

  •  Lacrimation