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Composition of different DDAVP minitablet formulations (F = formulation, DT = direct tableting, G + T = granulation + tableting, G + T + L = granulation + tableting + loss supplement).
| Substance | Amount (%)a |
||
|---|---|---|---|
| F1 (DT) | F2 (G + T) | F3 (G + T + L) | |
| Desmopressin acetate | 3.0 | 3.0 | 3.7 |
| Magnesium stearate | 3.0 | 3.0 | 3.0 |
| Kollidon 30b | – | 0.025 | 0.025 |
| Flowlac 100c | ad 100.0 | ad 100.0 | ad 100.0 |
(w/w).
Povidone with K = 30.
α-lactose monohydrate/amorphous lactose.
