Table 2.
Permeation of desmopressin was calculated for an area of 0.64 cm2 (MT and composite) and for an area of 0.38 cm2 (composite), mean ± SD, n = 3.
| Time (min) | Drug amount (ng/cm2) |
Percentage of applied dose (%) |
||||
|---|---|---|---|---|---|---|
| MT (0.64 cm2) | Composite (0.64 cm2) | Composite (0.38 cm2) | MT (0.64 cm2) | Composite (0.64 cm2) | Composite (0.38 cm2) | |
| 10 | 7.1 ± 7.5 | – | – | 0.004 ± 0.004 | – | – |
| 30 | 910.7 ± 90.7 | 175.5 ± 80.1 | 292.5 ± 133.4 | 0.46 ± 0.05 | 0.09 ± 0.04 | 0.15 ± 0.07 |
| 60 | 2664.3 ± 144.2 | 868.6 ± 168.4 | 1447.7 ± 280.7 | 1.38 ± 0.07 | 0.43 ± 0.08 | 0.72 ± 0.14 |