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. 2021 Jun 19;69:103453. doi: 10.1016/j.ebiom.2021.103453

Fig. 1.

Fig 1

Summary of DMG-immune system interactions. DMG is an immunologically cold tumor with very limited T cell and NK cell infiltration. Glioma associated macrophages consisting of bone marrow-derived macrophages and microglia are the primary immune cells that reside in the tumor microenvironment. Select chemokines and cytokines are also expressed in DMG.