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. 2021 Jun 23;43:25. doi: 10.1186/s41021-021-00195-1

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 2 — Packaging efficiencies of homozygous gpt delta rats. Two candidate WH homozygous gpt delta rat lines were analyzed for packaging efficiency. F344 heterozygous gpt delta rats were used as a control. Three animals were used in each group. Genomic DNA was extracted from the liver of untreated rats. Three independent in vitro packaging reactions using 10 µL DNA were conducted for each DNA sample. E. coli C and YG6020 cells were infected with the packaged phages. The number of rescued phages per packaging reaction (plaque forming unit: p.f.u or colony forming unit: c.f.u) was estimated. Error bar represents standard deviation