Table 3.
Treatment, complications and outcomes of patients with K. pneumoniae liver abscess with sepsis or without sepsis
| Characteristic | Total n = 135 |
KPLA with sepsis n = 37 |
KPLA without sepsis n = 98 |
P value |
|---|---|---|---|---|
| Complications | ||||
| Sepsis shock | 8 (5.9) | 7 (18.9) | 1 (1.0) | 0.000a |
| Acute Respiratory Distress Syndrome | 4 (3.0) | 4 (10.8) | 0 | 0.005a |
| Acute kidney injury | 2 (1.5) | 2 (5.4) | 0 | 0.074 a |
| Pleural effusion | 11 (8.1) | 4 (10.8) | 7 (7.1) | 0.493 a |
| Spontaneous bacterial peritonitis | 2 (1.5) | 2 (5.4) | 0 | 0.074 a |
| Metastatic infections | ||||
| Lung | 11 (8.1) | 9 (24.3) | 2 (2.0) | 0.000a |
| Eye | 4 (3.0) | 4 (10.8) | 0 | 0.005a |
| CNS | 1 (0.7) | 1 (2.7) | 0 | 0.274a |
| Others | 4 (3.4) | 3 (8.1) | 1 (1.0) | 0.063a |
| Hospital length of stay, days | 14.5 ± 9.0 | 20.7 ± 9.5 | 12.2 ± 7.7 | 0.000 |
| ICU admission | 14 (10.4) | 11 (29.7) | 3 (3.1) | 0.000a |
| Readmission | 8 (5.9) | 2 (5.4) | 6 (6.1) | 1.000a |
| Treatment | 0.696 | |||
| Antibiotics alone | 7 (5.2) | 1 (2.7) | 6 (6.1) | |
| Antibiotics+Percutaneous drainage | 122 (90.4) | 34 (91.9) | 88 (89.8) | |
| Antibiotics+Surgical drainage | 6 (4.4) | 2 (5.4) | 4 (4.1) | |
| Antibiotic drugs | ||||
| Beta-lactamase inhibitors | 38 (28.1) | 18 (48.6) | 20 (20.4) | 0.001 |
| The third generation of cephalosporin | 59 (43.7) | 18 (48.6) | 41 (41.8) | 0.477 |
| Fluoroquinolone | 51 (37.8) | 17 (45.9) | 34 (34.7) | 0.229 |
| Carbapenems | 96 (71.1) | 31 (83.8) | 65 (66.3) | 0.046 |
| Metronidazole | 57 (42.2) | 16 (43.2) | 41 (41.8) | 0.883 |
| Clinical outcomes | 0.074a | |||
| Cured | 133 (98.5) | 35 (94.6) | 98 (100) | |
| Died (Poor prognosis) | 2 (1.5) | 2 (5.4) | 0 | |