Table 4.
Reported data about pfhrp2, pfhrp3 and pfhrp2/3 deletions among RDT false
| Study | WHO region | N | HRP2-RDT sensitivity (%) | False negative rate (%) | Negative like-hood ratio | P (%) of pfhrp2 deletion (%) | P (%) of pfhrp3 deletion (%) | P (%) of pfhrp2/3 deletions (%) |
|---|---|---|---|---|---|---|---|---|
| Amoah et al. [74] | Africa | 38 | 72.66 | 27.33 | 0.49 | 15.79 | NR | NR |
| Berhane et al. [14] | Africa | 31 | 38 | 62 | NA | 100 | 100 | 100 |
| Berzosa et al. [21] | Africa | 122 | 84.38 | 15.62 | 0.18 | 75.41 | 78.69 | 66.39 |
| Beshir et al. [49] | Africa | 7 | 82.44 | 17.5 | 0.15 | 85.71 | 14.29 | NR |
| Bharti et al. [24] | Asia | 50 | 76 | NA | NA | 72.00 | 54.00 | 50.00 |
| Funwei et al. [69] | Africa | 31 | 88.53 | 9.11 | 0.001 | 25.81 | 12.90 | 12.90 |
| Gupta et al. [22] | Africa | 69 | 85.89 | 14.11 | 0.14 | 1.45 | NR | 0.0 |
| Koita et al. [28] | Africa | 26 | 95 | 5.16 | 0.063 | 38.46 | NR | 0.0 |
| Kobayashi et al. [52] | Africa | 69 | NA | 1.7 | NA | 4.35 | 0.00 | 0.0 |
| Kozycki et al. [11] | Africa | 140 | 91.8 | NA | NA | 22.86 | NR | NR |
| Kumar et al. [50] | Asia | 2 | 95.83 | 4.17 | NA | 100 | 100 | 100 |
| Maltha et al. [13] | South America | 21 | 71.60 | 28.38 | NA | 90.48 | 0.00 | 90.48 |
| Nderu et al. [9] | Africa | 91 | 93.8 | 6 | 0.08 | 0 | 0.00 | NR |
| Owusu et al. [47] | Africa | 138 | 80.78 | 20.97 | 0.002 | 4.35 | 5.80 | 4.35 |
| Parr et al. [46] | Africa | 783 | 71.55 | 28.45 | NA | 19.03 | NR | NR |
| Pati et al. [25] | Asia | 58 | 84.90 | 15.1 | 0.155 | 48.28 | 41.38 | 29.31 |
| Plucinski et al. [51] | Africa | 5 | 81 | NA | NA | 40.00 | NR | 20.00 |
| Thomson et al. [12] | Africa | 173 | 89.34 | 10.66 | 0.1368 | 5.20 | 1.73 | 1.73 |
| Willie et al. [30] | Africa | 8 | 96 | 12.9 | 0.144 | 0.00 | NR | NR |
| Wurtz et al. [16] | Africa | 7 | 94.07 | 5.90 | NA | 42.86 | 85.71 | 28.57 |
N sample size, P prevalence among RDT with negative results, NA not applicable, NR not reported