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. 2021 Jun 4;9:640336. doi: 10.3389/fchem.2021.640336

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Copyright © 2021 Kobayashi and Imai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Chromatograms corresponding to 8.0 µg of total protein obtained from six human colorectal cancer cell lines and a normal colorectal cell line after derivatization with DAABD-Cl. The peaks indicated by black arrows (1–14) differed in intensity between the cancer cell lines and the normal cell line. The peaks indicated by red arrows (a–l) differed in intensity between the metastatic cell lines and the non-metastatic cell line.