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. 2021 Jun 4;12:684233. doi: 10.3389/fmicb.2021.684233

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Copyright © 2021 Chen, Chou and Yang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of MAT on (A) total intestinal commensal bacteria at birth, (B) survival rate, (C) body weight at birth, and (D) body weight on postnatal day 7. MAT significantly reduced the number of commensal bacteria in newborn mice compared with that in the control newborns. The survival rates were comparable between the mice born to control and antibiotic-treated dams. The mice born to the antibiotic-treated dams exhibited significantly lower body weights at birth and on postnatal day 7 than that of the mice born to the control dams. ^*p < 0.05; ^***p < 0.001. MAT, maternal antibiotic treatment.