Figure 1. Patients with MIS-C Treated with Immunomodulatory Therapies in the Overcoming COVID-19 Surveillance Registry.
Among the 65 patients who received initial treatment with intravenous immune globulin (IVIG) plus glucocorticoids, followed by adjunctive treatment on or after day 1, adjunctive treatment consisted of a second dose of IVIG in 35 patients, a biologic alone in 16 patients, and a second dose of IVIG plus a biologic in 14 patients. Among the 121 patients who received initial treatment with IVIG alone, followed by adjunctive treatment on or after day 1, adjunctive treatment consisted of glucocorticoids alone in 63 patients; a second dose of IVIG in 15 patients; a biologic alone in 8 patients; glucocorticoids and a second dose of IVIG in 19 patients; glucocorticoids, a second dose of IVIG, and a biologic in 14 patients; and a second dose of IVIG and a biologic in 2 patients. MIS-C denotes multisystem inflammatory syndrome in children.