Fig. 5. (a, b) k_app as a function of [WT TtCarH] for a range of [AdoCbl] (see Table S3†). k₁ is not [WT]-dependent (a). k₂ is [WT]-dependent and the data from all [AdoCbl] were concatenated and fit linearly (b). (c and d) As panel (a and b) in all aspects but data are from the G192Q variant.