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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: FASEB J. 2021 Jul;35(7):e21732. doi: 10.1096/fj.202100385R

Figure 1.

Figure 1.

Effect of SMC‐specific Asah1 deletion on arterial stiffness in Vit D‐treated SMC specific Asah1 KO mice. (A) Representative Doppler images showed Doppler velocity signals. (B) Representative images of aortic sections showed damage to elastic fibers. (C, D) Summarized bar graph showing the effect of Torin-1 on the PWV and elastin breaks. n=5, SMC: smooth muscle cell; Vehl: vehicle; Vit D: vitamin D; Tor: Torin-1, ‘n’ is mouse number. *P < 0.05 vs WT/WT Vehl; #P < 0.05 vs WT/WT Vit D group; $P< 0.05 vs. Asah1fl/fl/SMCre Vit D group by one-way ANOVA with Holm-Sidak’s test post-hoc analysis. Data are shown as mean ± SEM of values.