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. Author manuscript; available in PMC: 2022 Jul 1.
Published in final edited form as: FASEB J. 2021 Jul;35(7):e21732. doi: 10.1096/fj.202100385R

Figure 10.

Figure 10.

Schematic model indicates that lysosomal Ac associated CER-mTOR signaling may regulate lysosome fusion with MVBs and exosome secretion which may represent a novel molecular mechanism involved in the development of AMC. Ac: Acid ceramidase; SMCs: Smooth muscle cells; AMC: Arterial medial calcification.