Fig. 1. General components of ABPs and AfBPs (A) and structures of commonly used reporter groups, bioorthogonal handles and photo-crosslinkers. (B) Examples of the reporter groups: cyanine fluorophore for visualization and biotin as an affinity tag. (C) Examples of commonly used bioorthogonal handles in ABPP. (D) Examples of photo-crosslinkers that are commonly used in ABPP. (E) Examples of photo-crosslinkers with bioorthogonal handles for AfBPs.
