Fig. 15. Use clickable AfBPs to capture proteins associated with PARylation. (A) Structures of reported bifunctional NAD+ probes. (B) Schematic illustration of the process for capturing PARylation-related interacting proteins using a bifunctional NAD+ probe. Reproduced from ref. 135 with permission from American Chemical Society, copyright 2021. (C) Structures of reported BAD-based clickable AfBPs.
