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. 2021 May 18;12(24):8288–8310. doi: 10.1039/d1sc01359a

Fig. 16. Ub-based ABPs and AfBPs for DUBs and E1, E2, E3 enzyme studies. (A) Structures of reported ABPs and AfBPs based on Ub. (B) Mechanism of 62 for the labeling of E1, E2 and E3 enzymes. Pathway (1): enzymatic covalent binding process, pathway (2): natural trans–trans thioesterification process.

Fig. 16