Table 4. Association betwe and cardiovascular function.

i) Outcome: E/A<=0.9.

Current metabolites	Events/total	OR (95% CI)	p-value	Adjusted OR (95%)*	Adjusted p-value*
Short chain
C3	142/207	1.0 (1.0, 1.002)	0.62	-	-
C4	142/207	1.0 (1.0, 1.001)	0.26	-	-
C4-OH	142/207	1.03 (1.001, 1.06)	0.045	1.02 (0.99, 1.05)	0.25
C5	142/207	1.001 (0.99, 1.009)	0.89	-	-
C5:1	139/202	0.97 (0.93, 1.02)	0.29	-	-
Medium chain
C10:1	137/195	1.002 (1.0, 1.008)	0.42	-	-
C10:2	112/168	1.03 (0.99, 1.07)	0.15	-	-
C12-OH/C10-DC	142/207	1.53 (1.11, 2.10)	0.009	1.50 (1.07, 2.09)	0.018
C8:1-OH/C6:1-DC	142/207	0.99 (0.97, 1.01)	0.45	-	-
C8-DC	142/207	1.01 (0.99, 1.04)	0.29	-	-
Long chain
C14:1-OH	142/207	1.03 (0.97, 1.09)	0.38	-	-
C14:3	142/207	1.06 (0.94, 1.20)	0.35	-	-
C14-OH/C12-DC	142/207	1.13 (1.02, 1.25)	0.016	1.11 (1.0, 1.24)	0.052
C16	142/207	1.02 (1.007, 1.03)	0.002	1.02 (1.008, 1.03)	0.002
C16:1-OH/C14:1-DC	142/207	1.16 (0.99, 1.36)	0.067	-	-
C16:2-OH	142/207	1.06 (0.90-1.25)	0.48	-	-
C16:3-OH/C14:3-DC	136/199	1.12 (0.79-1.60)	0.52	-	-
C16-OH	142/207	1.07 (0.97, 1.19)	0.19	-	-
C18	142/207	1.03 (0.99, 1.06)	0.12	-	-
C18:1	142/207	1.01 (1.0, 1.02)	0.043	1.01 (1.0, 1.02)	0.046
C18:1-OH/C16:1-DC	142/207	1.23 (1.03, 1.46)	0.022	1.20 (1.0, 1.43)	0.054
C18:2	142/207	1.008 (0.99, 1.02)	0.31	-	-
C18:3	139/203	1.05 (0.92, 1.21)	0.46	-	-
C18-OH/C16-DC	142/207	1.22 (1.04, 1.42)	0.014	1.19 (1.01, 1.41)	0.038
C20	142/207	1.05 (0.88, 1.25)	0.60	-	-
C20:1	142/207	0.97 (0.87, 1.10)	0.68	-	-
C20:1-OH/C18:1-DC	142/207	1.06 (0.97, 1.15)	0.19	-	-
C20:2	142/207	0.97 (0.80, 1.19)	0.80	-	-
C20:2-OH/C18:2-DC	141/206	1.04 (0.81, 1.33)	0.76	-	-
C20:3	142/207	1.09 (0.95, 1.26)	0.22	-	-
C20:3-OH/C18:3-DC	132/194	0.86 (0.58, 1.29)	0.47	-	-
C20:4	142/207	1.03 (0.89, 1.20)	0.68	-	-
C22:1	142/207	0.98 (0.84, 1.14)	0.80	-	-
C22:2	137/197	1.36 (0.72, 2.56)	0.35	-	-
C22:4	140/203	1.11 (0.69, 1.77)	0.67	-	-
C22:5	141/205	1.06 (0.74, 1.50)	0.76	-	-

*adjusted for diabetes mellitus, female, BMI, CV rf>2.