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. 2021 Jun 23;129(6):067006. doi: 10.1289/EHP8610

Table 2.

Endocrine active chemicals aggregated in at least 0.1% of household-months.

Aggregate endocrine active chemical Household-months with aggregation % of Total household-months (539,827) Mean number of products per household-month Receptor action
Decamethylcyclopentasiloxane 6402 1.19 (%) 2.27 Other
Propylparaben 3975 0.74 (%) 2.24 Estrogen
Linalool 3380 0.63 (%) 2.27 Other
2-Hydroxy-4-methoxybenzophenone 2679 0.50 (%) 2.20 Androgen
Benzyl acetate 2203 0.41 (%) 2.39 Other
1-Cedr-8-en-9-ylethanone 2079 0.39 (%) 2.18 Androgen
Diphenyl oxide 2063 0.38 (%) 2.2 Other
1-Tetradecanamine, N,N-dimethyl-, N-oxide 1411 0.26 (%) 2.16 Androgen
Methylparaben 1376 0.25 (%) 2.24 Other
Limonene 1191 0.22 (%) 2.16 Other
Benzethonium chloride 855 0.16 (%) 2.48 Estrogen
Dl-tocopherol mixture 810 0.15 (%) 2.13 Androgen
Behentrimonium methosulfate 633 0.12 (%) 2.12 Androgen
Diazolidinyl urea 559 0.10 (%) 2.18 Androgen

Note: Aggregation is defined as occurring in two or more of a household’s purchased products in a single month. Chemicals labeled “Other” in the Receptor Action column are those appearing in the literature curated list (Dodson et al 2012) but not predicted to have endocrine receptor (ER) or androgen receptor (AR) activity in the Collaborative Estrogen Receptor Activity Prediction Project (CERAPP) or Collaborative Modeling Project for Androgen Receptor Activity (CoMPARA) studies.