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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: J Biomed Mater Res B Appl Biomater. 2020 Aug 21;109(3):338–347. doi: 10.1002/jbm.b.34703

FIGURE 8.

FIGURE 8

(a) Results from the Kirby-Bauer assay (n = 5) showed that empty gels, autoclaved and nonautoclaved, did not have antimicrobial activity. In addition, the vancomycin in both autoclaved and nonautoclaved P407 was as effective as vancomycin delivered in phosphate buffered saline (PBS). The vehicles (nonautoclaved P407, autoclaved P407, and PBS) loaded with vancomycin produced zones of inhibition that were significantly different than the blank autoclaved and nonautoclaved P407 (*p < .05, ND: not detected). (b) Colony forming units per milliliter 24 hr post-treatment (n = 5–6). Nonautoclaved P407, nonautoclaved P407 + vancomycin (vanco), autoclaved P407 + vancomycin, and PBS + vancomycin were significantly different from no treatment (*p < .05) but not significantly different from each other. CFU, colony forming units