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Supplementary Table 1.

GRADE quality

Author Study Design Risk of Bias Inconsistency Indirectness Imprecision Publication Bias Large Effect Plausible Confounding Quality
Hu et al Retrospecitve
Case Series
Low Not serious Not serious Not serious Serious N/A No ⊕⊕⊕ ⊕
High
Encinas-Ullán et al Prospective
Case Control
Low Not serious Not serious Serious Not serious N/A No ⊕⊕⊕
Moderate
Choi et al Retrospective
Case Series
Moderate Not serious Not serious Not serious Undetected N/A No ⊕⊕⊕
Moderate
Boraiah et al Retrospective
Case Series
Moderate Not serious Not serious Not serious Undetected N/A No ⊕⊕⊕
Moderate
Sirkin et al Retrospective
Case Series
Moderate Not serious Serious Not serious Not serious N/A No ⊕⊕⊕
Moderate
Bone et al Prospective
Case Series
Moderate Serious Not serious Serious Undetected N/A No ⊕⊕
Low
Molina et al Retrospective
Case Series
Moderate Not serious Serious Not serious Serious N/A No ⊕⊕⊕
Moderate
White et al Cohort Moderate Not serious Not serious Serious Undetected N/A No ⊕⊕⊕
Moderate
Gardner et al Retrospective
Case Series
Moderate Not Serious Not Serious Not Serious Undetected N/A No ⊕⊕⊕
Moderate
Gehr et al Prospective
Case Series
Moderate Serious Not Serious Not Serious Serious N/A No ⊕⊕
Low
Danoff et al Retrospective
Case Series
Low Not Serious Serious Not Serious Serious N/A No ⊕⊕⊕
Moderate
Silluzio et al Retrospective
Case Series
Moderate Not Serious Not Serious Serious Undetected N/A No ⊕⊕⊕
Moderate
Zeng et al Retrospective
Case Series
Moderate Not Serious Not Serious Serious Not Serious N/A No ⊕⊕⊕
Moderate
Conroy et al Retrospective
Case Series
Moderate Not Serious Serious Serious Serious N/A No ⊕⊕⊕
Moderate
Harris et al Retrospective
Case Series
Moderate Not Serious Serious Not Serious Serious N/A No ⊕⊕⊕
Moderate
Kapukaya et al Retrospective
Case Series
Low Not Serious Not Serious Serious Undetected N/A No ⊕⊕⊕ ⊕
High
Yildiz et al Retrospective Case Series Moderate Not Serious Not Serious Not Serious Undetected N/A No ⊕⊕⊕
Moderate
Wyrsch et al Randomised
Controlled Trials
High Not Serious Not Serious Not Serious Undetected N/A No ⊕⊕⊕
Moderate

“Very low”; the true effect is probably markedly different from the estimated effect, “Low”; the true effect might be markedly different from the estimated effect, “Moderate”; the authors believe that the true effect is probably close to the estimated effect, “High”; the authors have a lot of confidence that the true effect is similar to the estimated effect