. Author manuscript; available in PMC: 2021 Jun 23.

Published in final edited form as: Int J Obes (Lond). 2018 May 17;43(3):468–474. doi: 10.1038/s41366-018-0106-1

Table 3.

Differences in the 6-year change of adiposity measures per allele of rs752579 according to baseline intake of food source B-vitamins

	Tertile of food source B-vitamins intake

	T1	T2	T3	p for interaction
BMI change in 6 years
Folate	−0.29 ± 0.11	0.06 ± 0.09	0.11 ± 0.11	0.003
Vitamin B₂	−0.25 ± 0.10	−0.01 ± 0.11	0.15 ± 0.10	0.011
Vitamin B₆	−0.17 ± 0.11	−0.16 ± 0.10	0.21 ± 0.10	0.001
Vitamin B₁₂	−0.12 ± 0.11	−0.23 ± 0.10	0.26 ± 0.11	0.009
Weight change in 6 years
Folate	−0.59 ± 0.29	0.11 ± 0.26	0.31 ± 0.28	0.011
Vitamin B₂	−0.89 ± 0.40	−0.52 ± 0.28	−0.01 ± 0.29	0.024
Vitamin B₆	−0.27 ± 0.29	−0.46 ± 0.26	0.60 ± 0.28	0.007
Vitamin B₁₂	−0.18 ± 0.28	−0.55 ± 0.26	0.63 ± 0.29	0.016

Data are β ± SE. The general linear model was used to test the genetic association of baseline food source vitamin B intake with 6-year change in adiposity measures after adjustment for age, smoking, drinking, alternative health eating index, total energy intake, physical activity, calcium and vitamin D intervention, and diet modification intervention, and other B-vitamins (mutually adjusted). SNP was treated as a continuous variable when calculating the p-value for interaction