Table 2. Summary of the main characteristics of the eligible studies.
| Author, year | Age (years) | Total number of patients | Sex | Groups | Time of medication administration | Postoperative medication | Excluded patients | Complications | Patients who did not return |
|---|---|---|---|---|---|---|---|---|---|
| Degirmenci, and Yalcin (24) | 18-24 | 40 | Group 1 M: 6 F: 14 Group 2 M: 4 F:16 |
Group 1: oral placebo+intravenous placebo Group 2: oral placebo+intravenous ibuprofen 400 mg |
60 min before and infusion 30 min before | Group 1: paracetamol 500 mg every 8h for 6 days Group 2: paracetamol 500 mg every 8h for 6 days |
G 1: 2 G 2: 2 |
G 1: 2 G 2: 1 |
G 1: -- G 2: -- |
| Demirbas et al. (7) | Mean: 25.1 | 50 | -- | Group 1: 800 mg of intravenous ibuprofen 60 min before surgery and intravenous placebo (100 mL of saline) 60 min after surgery Group 3: intravenous placebo (100 mL of saline) 60 min before and after surgery |
60 min before surgery | Acetaminophen 500 mg | G 1: 0 G 3: 0 |
G 1: -- G 3: -- |
G 1: 0 G 3: 0 |
| Küpeli and Gülnahar (25) | 20-35 | 40 | Group 2 M: 8 F: 12 Group 3 M:8 F:12 |
Group 2: preoperative intravenous infusion including Ibuprofen 800 mg for 30 min Group 3: preoperative intravenous infusion of placebo (normal saline) for 30 min |
15 min before surgery | Infusion of dexketoprofen+methylprednisolone (Prednol-L; Mustafa Nevzat, Istanbul, Turkey) 40 mg+sultamicillin sulfate (Ampisid; Mustafa Nevzat) in 150 mL of normal saline | G 2: -- G 3: -- |
G 2: -- G 3: -- |
G 2: -- G 3: -- |
M, male; F, female; G 1, group 1; G 2, group 2; G 3, group 3; --, not mentioned in the manuscript; Paracetamol = Acetaminophen.