Figure 2.

Intact intrinsic excitability of ITNs in the M1 L5b following the loss of midbrain DA neurons. A, B, Representative graphs showing the injection site of green Retrobeads in the dorsal striatum (A) and retrogradely labeled M1 L5b ITNs (B). C, D, Representative spikes trains evoked by somatic current injections into ITNs from controls and 6-OHDA mice (C) and the frequency-current relationship of ITNs from controls and 6-OHDA mice (D). E–H, Boxplots showing a similar rheobase (E), an unaltered gain of spike-current curve (F), firing frequency in response to maximal current injections (i.e., 720 pA; G), and spike adaptation (H) between ITNs from 6-OHDA mice and controls. ns, not significant, MWU.