Table 3.
Infection rates and adjusted HRs for PCR-positive infection after the first dose of either vaccine, by days since vaccination (primary analysis)
| Person-days at risk | PCR tests | PCR testing rate per 1000 person-days | Infection events | Infection rate per 10 000 person-days | Adjusted HR (95% CI) | p value | |
|---|---|---|---|---|---|---|---|
| Unvaccinated | 338 003 | 15 392 | 45·54 | 723 | 21·39 | 1 (ref) | .. |
| 0–6 days | 47 591 | 2482 | 52·15 | 105 | 22·06 | 0·64 (0·38–1·06) | 0·083 |
| 7–13 days | 53 511 | 3189 | 59·60 | 139 | 25·98 | 0·83 (0·54–1·28) | 0·404 |
| 14–20 days | 50 362 | 2462 | 48·89 | 132 | 26·21 | 0·96 (0·57–1·60) | 0·866 |
| 21–27 days | 47 514 | 2478 | 52·15 | 95 | 19·99 | 0·92 (0·53–1·59) | 0·762 |
| 28–34 days | 43 136 | 2078 | 48·17 | 42 | 9·74 | 0·44 (0·24–0·81) | 0·0087 |
| 35–48 days | 63 012 | 4681 | 74·29 | 59 | 9·36 | 0·38 (0·19–0·77) | 0·0069 |
| ≥49 days | 27 499 | 3590 | 130·55 | 40 | 14·55 | 0·49 (0·20–1·17) | 0·108 |
| Overall | 670 628 | 36 352 | 54·21 | 1335 | 19·91 | .. | .. |
Adjusted HRs were estimated using Cox proportional hazards regression according to days since the first vaccine dose; the comparator was the unvaccinated group. HRs are adjusted for age, sex, local monthly infection incidence, and long-term care facility bed capacity. 95% CIs were calculated using robust standard errors for long-term care facility-level effects. HR=hazard ratio.