Table 1. Summary characteristics of included articles.
Characteristic | Studies n (%) |
---|---|
Geographic scope | |
National | 116 (12%) |
Regional | 347 (36%) |
Local | 277 (29%) |
Sublocal | 228 (24%) |
Age groupsa | |
Children and Youth (0–17 years) | 28 (3%) |
Adults (18–64 years) | 268 (28%) |
Seniors (65+ years) | 7 (0.7%) |
Multiple age groups | 609 (63%) |
Population | |
Studies reporting population-wide estimates | 590 (61%) |
Studiesreporting population-specific estimatesb | 378 (39%) |
County income levelc | |
High income | 747 (77%) |
Low/middle income | 221 (23%) |
Sampling method | |
Probability sampling | 209 (22%) |
Non-probability sampling | 759 (78%) |
Antibody testsd | |
ELISA | 242 (25%) |
CLIA | 409 (42%) |
LFIA | 137 (14%) |
Other | 10 (1%) |
Neutralization | 4 (0.4%) |
Multiple types | 37 (4%) |
Antibody isotypes reportedd | |
IgG | 845 (87%) |
IgM | 227 (24%) |
IgA | 47 (5%) |
Risk of bias | |
Low | 28 (3%) |
Moderate | 443 (46%) |
High | 424 (44%) |
Unclear | 73 (8%) |
aWhen the age range for participants in a study overlapped multiple age categories by > = 30% then the study was counted as examining multiple age groups.
bStudies sampling from well-defined population sub-groups.
cClassified according to the WHO global burden of disease region groupings (high vs other—low/middle).
dStudies could have met multiple criteria so the sum of percentages may exceed 100%. Abbreviations: ELISA = enzyme-linked immunosorbent assay; CLIA = chemiluminescence immunoassay; LFIA = lateral flow immunoassay.