TABLE 2.

Secondary End Points

Criteria	Duloxetine	Pregabalin	Pregabalin + Duloxetine	P value
	(n = 77)	(n = 77)	(n = 20)
Weight change, %	−0.3	1.5	+2.0	.18
Weight change after at least 12 months, lb	−0.9	+3.6	+8.5	.05
Hemoglobin A1c change in and patients with prediabetes or diabetes mellitus, %	(n = 43)	(n = 50)	(n = 12)
	−0.1	+0.3	−0.3	.14
Weight change for patients prescribed duloxetine > 60 mg/d or pregabalin > 300 mg/d, lb	(n = 13)	(n = 21)
	−2.8	+6.5	---	.05
Weight change for patients in Managing Overweight Veterans Everywhere program, lb	(n = 10)	(n = 8)	(n = 5)
	+1.5	+4.9	+3.4	.91