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. 2021 Jun 15;2021:8836078. doi: 10.1155/2021/8836078

Figure 4.

Figure 4

LncRNA MALAT1/miR-124 axis regulates the proliferation of cervical tumor cells. (a–d) Cell viabilities and numbers of control, miR-124, and NC (negative control) groups were determined by CCK-8 assays and trypan blue staining, n = 5,∗∗p < 0.01 and ∗∗∗p < 0.001 compared with the control group. ##p < 0.05, #p < 0.01, and ###p < 0.001 compared with the miR-124 group. (e–h) Linear correlation of cervical cancer cell proliferation was analyzed with miR-124 level in Hela, Caski, C-33A, and SiHa cell lines. (i, j) Cell viabilities and numbers of NC (negative control of miR-124), miR-124, miR-124 + LV-MALAT1, and miR-124 + LV-NC groups were determined by CCK-8 and trypan blue staining assays, respectively. n = 3 in each batches, ∗∗∗p < 0.001 compared with the NC group, ###p < 0.001 compared with the miR-124 group, and $$$p < 0.001 compared with the miR-124 + LV-MALAT1 group. (k, l) Cell viabilities and numbers of LV-shNC, LV-shMALAT1, LV-shMALAT1 + AMO-124, and LV-shMALAT1 + AMO-NC groups were determined by CCK-8 and trypan blue staining assays, respectively. n = 3 in each batches, ∗p < 0.05 and ∗∗∗p < 0.001 compared with the LV-shNC group, #p < 0.05 and ###p < 0.001 compared with the LV-shMALAT1, and $p < 0.05 and $$$p < 0.001 compared with the LV-shMALAT1 + AMO-124 group.