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. 2021 Mar 2;14(4):923–936. doi: 10.1038/s41385-021-00386-7

Fig. 2. Lack of IL-33 or ST2 alleviates C. rodentium-induced intestinal inflammation.

Fig. 2

a Body weight changes relative to initial weight in St2−/− and WT non-infected and CR-infected mice monitored during the course of the experiment. Statistical analyses were performed using two-way ANOVA followed by Bonferroni’s post hoc test. b Representative pictures (scale bars 100 µm) of H&E-stained colon sections (left) and histopathological score (right). Each parameter of colon damage and inflammation is shown as mean ± SEM. Statistical analyses were performed using Mann–Whitney U test or Student’s t test to compare St2−/− groups with their respective WT control groups. Results from two independent experiments are shown (n = 4–6 per group). c Body weight changes relative to initial weight in Il33−/− and WT non-infected and CR-infected mice. Statistical analysis was performed using two-way ANOVA followed by Bonferroni’s post hoc test. d Representative pictures (scale bars 100 µm) of H&E-stained colon sections (left) and histopathological score (right). Middle and distal colon portions were assessed for damage and inflammation as before. Bars show the mean ± SEM of each parameter. Statistical analysis was performed using Mann–Whitney U test or Student’s t test to compare Il33−/− groups with their respective WT control groups (n = 3 mice per group). *P < 0.05; **P < 0.01; ***P < 0.001.