Table 3.
Acceptability of the dapivirine vaginal ring based on use in the past 3 months, at month-3 visit and PUEV
| Month 3 | PUEV | |||
|---|---|---|---|---|
| N | (%) | N | (%) | |
| Total who used ring in past 3 monthsa | 2334 | (100) | 2075 | (100) |
| Use attributes: ease and comfort of use | ||||
| How difficult was it to insert the ring?b | ||||
| Very/somewhat difficult | 346 | (15) | 128 | (6) |
| Not difficult at all | 1974 | (85) | 1938 | (93) |
| How difficult was it to take the ring out?b | ||||
| Very/somewhat difficult | 326 | (14) | 197 | (10) |
| Not difficult at all | 1776 | (76) | 1617 | (78) |
| Never took out ring in past 3 months | 232 | (10) | 261 | (13) |
| Use attributes: physical sensation in situ | ||||
| How did it feel to have the ring inside you every day?b | ||||
| Usually comfortable | 2047 | (88) | 1907 | (92) |
| Sometimes/usually uncomfortable | 286 | (12) | 167 | (8) |
| Were you aware of the ring during normal daily activities?b | ||||
| Most/some of the time | 478 | (21) | 342 | (16) |
| Never | 1855 | (80) | 1732 | (84) |
| Effects on sex | ||||
| Total who had sex in past 3 months | 2310 | (99) | 2011 | (97) |
| How often did you feel the ring during sex? | ||||
| Most/some of the time | 592 | (26) | 474 | (24) |
| Never | 1716 | (74) | 1537 | (76) |
| Did any of your partners feel the ring during sex?b | ||||
| Yes | 444 | (19) | 348 | (17) |
| No | 1600 | (69) | 1389 | (69) |
| Don’t know | 265 | (12) | 273 | (14) |
PUEV product use end visit
aA total of 2474 participants had ACASI data available from Month 3, and 2270 from PUEV. PUEV ACASI data were missing from 2 sites due to transmission errors
bSignificant difference between Month-3 and PUEV (p < 0.05). Differences over time were tested using mixed-effect regression models, controlling for country, treatment arm, and number of months of follow-up