Vaginal Microbiome Change from Off-Menses to On-Menses
The lines in each plot connect the means of the relative abundance of specific bacteria from off- to on-menses. Trends seen in this figure suggest two findings. First, compared to the “mild localized pain” phenotype group, the “multiple severe symptom” phenotype group had a larger shift in lactobacilli and non-lactobacilli abundance from off- to on-menses. Second, from off- to on-menses, women with the “multiple severe symptoms” phenotype had a larger decrease in the Lactobacillus spp. relative abundance and a larger increase in Prevotella and Gardnerella.